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PhIND (Physiopathology and Imaging of Neurological Disorders, UMR-S 1237) is directed by Denis Vivien, professor in Neuroscience (PRE2) at University of Caen (France), and is a leading group in the field of stroke, with a large experience of collaborative projects including EU networks. PhIND is hosted in GIP CYCERON, one of the three centers in which PET was developed in France. Today, CYCERON is one of the few biomedical imaging platforms where neuroscience research is conducted on multiple levels that span from the molecule to the entire living human brain, including the synthesis of innovative imaging agents targeting adhesion molecules. Denis VIVIEN is currently co-coordinator of the European Marie Curie International Training Network “NeuroInflammation”.

The diverse areas of PhIND expertise create a highly synergistic environment to promote:

- The development of innovative methods and investigation tools, focusing on molecular biology, cell biology, physiology, behaviour and brain imaging,

- The application of these tools to push the boundaries of the study of the mechanisms underlying the functions and dysfunctions of the nervous system with a special interest for a set of common determinants of neurological disorders such as serine proteases (especially tPA), inflammatory processes and aging,

- The interaction between basic research and clinical practice, with a “bench to bed/bed to bench” approach.

The team members working on the MARVELOUS project are Maxime Gauberti, Benjamin Gory, Benoit Haelewyn, Mikael Naveau, Cyrille Orset, Emmanuel Touzé, and Denis Vivien (team leader).